[ Title ]
- Companion diagnostics for the targeted therapy of gastric cancer
[ Journal ]
- WORLD JOURNAL OF GASTROENTEROLOGY
[ Author ]
- Yoo, C Park, YS
[ Abstract ]
- Gastric cancer is the fourth most common type of cancer and represents a
major cause of cancer-related deaths worldwide. With recent biomedical
advances in our understanding of the molecular characteristics of
gastric cancer, many genetic alterations have been identified as
potential targets for its treatment. Multiple novel agents are currently
under development as the demand for active agents that improve the
survival of gastric cancer patients constantly increases. Based on
lessons from previous trials of targeted agents, it is now widely
accepted that the establishment of an optimal diagnostic test to select
molecularly defined patients is of equal importance to the development
of active agents against targetable genetic alterations. Herein, we
highlight the current status and future perspectives of companion
diagnostics in the treatment of gastric cancer.
[ URL ]
- http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS&DestLinkType=FullRecord;UT=WOS:000363267300003